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Research Interests:

My research interests focus on life span development and aging, particularly the coaction and interplay of genes and environments on cognitive aging and the risk of Alzheimer's disease and related dementias (ADRD). I engage in longitudinal research, often of twins and adoptees, to examine how and why individuals differ in early life contexts and behavioral health pathways across time and their effects on cognitive functioning. Cognitive resilience in the face of genetic and environmental risks is a current direction of interest. In addition to participating in the international Interplay of Genes and Environment Across Multiple Studies (IGEMS) consortia, and the Vietnam Era Twin Study of Aging (VETSA), I am the contact PI of the Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging (CATSLife).

Active Grants:

• R01 AG046938 (Reynolds, Wadsworth) 09/15/2020 - 05/31/2025. Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife2). Role: MPI, Contact
• R01 AG050595��(Kremen, Franz, Panizzon, Elman, Reynolds, MPIs, 2023-present). 06/01/20-03/31/25. The VETSA Longitudinal Twin Study of Cognition and Aging (VETSA 4). Role: MPI; Site PI
• R01 AG060470��(Gatz, Pedersen, MPIs) 09/01/2018 – 03/31/2025 [extension]. Clarifying risk and protective factors for dementia with the Interplay of Genes and Environment in Multiple Studies (IGEMS) consortium.��Role: Co-investigator; Site PI
• 1R21AG087486 (Luczak) 12/2024 ‐ 11/2026. Implications of midlife alcohol use for risk of dementia in male and female twins: Unique contributions and interactions with APOE4. Role: Co-investigator
• R01DA059804 (Gustavson) 08/15/2024- 5/31/2029. Establishing if Music Engagement is a Protective Factor in Adolescent Substance Use Using Existing Longitudinal, Genetic, and Environmental Datasets. Role: Co-investigator
• R01AG089666 (Reynolds, Neiderhiser) 08/01/2024 ‐ 04/30/2029. Gene-environment interplay among modifiable factors for AD/ADRD: risk and resilience across the lifespan. Role: Principal investigator, Contact
• 1R01AG081248 (Finch, Finkel, Gatz, MPI) 04/2024 ‐ 03/2029. Country, cohort, and gender disparities in the relationship between education and ADRD. Role: Co-investigator
• AG050595 (Panizzon (Contact), Elman, Franz, Panizzon, Reynolds, MPIs) 09/2015 – 03/2025. The VETSA Longitudinal Twin Study of Cognition and Aging (VETSA 4) Role: MPI
• FORTE Project Number: 2022-00672 (Karlsson, PI) 01/01/2023 –12/31/2025. Övervikt, en heterogen fenotyp: Undersökning av skillnader för att förstå sambandet med åldersrelaterade sjukdomar [Overweight as a heterogeneous phenotype: Leveraging differences in adiposity-related traits to understand effects on age-related disease]. Role: Collaborator.
• AFAR Application #HEV~NI23013 (Evans) 12/2023 – 12/2026. Gene-Gene Interaction Associations with Frailty to Identify Core Genes of Aging and Their Biological Context. Role: Co-investigator.

Additional Resources:

• Current CV
• Colorado Adoption/Twin Study of Lifespan Behavioral Development and Cognitive Aging (CATSLife)
• Life-BBR