Instrumentation

Acknowledgement

Please acknowledge the Proteomics and Mass Spectrometry Core Facilityin publications and talks. It is a requirement of funding agencies and CRUCIAL FOR FUTURE FUNDING.

We acknowledge Dave McCall in the Proteomics and Mass Spectrometry Core Facility (RRID: SCR_ 018992) in the Department of Biochemistry at the ÀÖ²¥´«Ã½ for data acquisition and analysis using the Waters Select Series Cyclic IMS mass spectrometer, funded by NIH 1S10OD038278-01.
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We acknowledge the Proteomics and Mass Spectrometry Core Facility (RRID: SCR_ 018992) in the Department of Biochemistry at the ÀÖ²¥´«Ã½ for data acquisition and analysis using the Thermo Orbitrap Q-Exactive HF-X, funded by NIH S10-OD025267

An RRID is a unique reference tag associated with a specific research resource. Robust metrics tracked by an RRID in publications enable the metrics needed for requesting new instrument funding and promotes meticulous rigor and reproducibility of research results.

The Central Analytical Laboratory facility, located in room C1B90 in the JSC Biotechnology Building, currently houses several Waters UPLCs and five mass spectrometers to provide structural information on various samples (from small organic molecules to large proteins). The facility is available to analyze samples from the both University of Colorado and non-CU sources.

The following instruments are housed in the facility:

ManufacturerModelMass AnalyzerIonization Methods
ShimadzuMALDI-7090-TOF/TOFMALDI-TOF/TOFMALDI
ThermoOrbitrap Q-Exactive HF-XQuadrupole-OrbitrapESI, nanospray
ThermoOrbitrap Exploris 480Quadrupole-OrbitrapESI, nanospray
ThermoISQ GCMSSingle QuadrupoleEI
WatersCyclic IMSQuadrupole/ToFESI

Our instruments are used to confirm the identity of various organic and inorganic compounds including liquid crystals, carboranes, proteins, peptides, oligonucleotides using both positive and negative ionization modes.

Contact Chris Ebmeier for further details.

Make A Reservation

For any users whoÌýhave been trainedÌýon sample preparation and instrument usage, reservations can be made to allow necessary instrument time.Ìý Currently, we are accepting online reservations for the following instruments only:

  • Thermo ISQ GCMS
  • Shimadzu MALDI-TOF/TOF
  • Waters Cyclic IMS
  • Waters HDX nanoUPLC

To access the reservation website using your Identikey + CU password.